It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. Reply. Do not use on cats. Radio-labeled fipronil was not detected in the dermis or the hypodermis (adipose tissue). Ivermectin for cattle *2. Fipronil 0.25 % w/v ... (flea allergy dermatitis) and lice in Dogs and Cats. * Fiproclear 402mg spot-on solution for very large dogs (40-60kg): 1 pipette of 4.02ml is sufficient for the treatment of a dog with a body weight of 40kg up to 60kg corresponding to a recommended minimum dose of 6.7mg fipronil/kg body weight. | P SC . (based on 60mg per 1ml potency*. Dosage: To moisten the coat as far as the skin, apply 3 to 6 mL per kg of body weight (i.e. GI parasites, levamizole drug of choice for lungworm . Dosing is based on weight. National regulatory authorities determine whether a product is approved for a given indication , i.e. The IHC Group. Concerns About Fipronil. Active substance: Fipronil 2.5 mg. Excipients: For the full list of excipients, see section 6.1. This product is used in both dogs and cats. The effects of fipronil and methoprene lasts about 30 days and remains effective after bathing or swimming though shampooing should be avoided within 48 hours of application. use on a particular host at a specific dose and against a specific parasite . use on a particular host at a specific dose and against a specific parasite . Fipronil and methoprene should not be used in animals with known hypersensitivity or allergy to the drug. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with fipronil. Le fipronil est une substance active de produit phytosanitaire (ou produit phytopharmaceutique, ou pesticide) et d'antiparasitaire vétérinaire, qui présente un effet insecticide et acaricide. The highest dose was reduced to 2 mg/kg bw per day after 38 days because of toxicity. 640 mg/kg LD50 acute, chicken, p.o. Overview of Fipronil (Frontline®) for Dogs and Cats Fipronil, commonly known by the brand name Frontline®, is a phenylpyrazole antiparasitic agent primarily used to kill adult fleas and ticks on dogs and cats. Product Names Product Images Check Price #1 SENTRY Fiproguard for Cats, Flea and Tick Prevention for Cats (1.5 Pounds and Over), Includes 6 Month Supply of Topical Flea Treatments. The chronic reference dose (RfD) for fipronil is 0.0002 mg/kg/day based on the NOAEL for chronic toxicity ... A spot-on treatment study with 14 C-fipronil on dogs and cats found that radio-labeled fipronil was distributed primarily in the superficial skin layers. Animals with long hair need the higher dose. No known incompatibilities exist for the use of concurrently administered medicinal products. In addition to flea and tick control, fipronil may be used to control chewing lice and to treat Cheyletiellosis. Fipronil spot-on is sold as separate canine and feline formulas, with the specific dosage based on the animal’s body weight. Mange and adjunct to myiasis therapy . Fipronil is used in a wide variety of pesticide products, including granular products for grass, gel baits, spot-… This drug is registered for use in animals only. Target species: Cats and Dogs Routes of administration: Manual spray gun for external use only. Topical spray containing 0.25% fipronil applied to dogs at 1x, 3x and 5x recommended dose for a total of 6 applications each 28 days apart (DOG CLI 138). Volume of unit dose (ml) Fipronil (mg) S-methoprene (mg) Amitraz (mg) dogs 2-10 kg . However, if your dog weighs more than 132 pounds, you’ll need to combine products to get the correct dosage. Additionally, if you treat your dog with Frontline more often than the recommended 30 days, he (or she) can be getting too much medicine. Effipro will cover dogs against fleas for 8 weeks, and against ticks for 4 weeks. The lowest dose that produced Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. Eighteen dogs were randomly assigned to the following treatment groups (n = 6): (1) 65% permethrin, (2) 9.7% fipronil, or (3) untreated control. When test animals have eaten fipronil, between 15 and 33% (goats) and 30 to 50% (rats) of the ingested dose was absorbed by the body. 9.78%. Be certain to complete the prescription unless specifically directed by your veterinarian. Dogs up to 22 pounds should be treated with one 0.67 ml pipette of topical solution, dogs 23 to 44 pounds should use one 1.34 ml pipette, dogs 45 to 88 pounds need one 2.68 ml pipette, and dogs weighing 89 to 132 pounds should be treated with one 4 ml pipette. For use on dogs and puppies 8 weeks of age or older and weighing 4 lbs or greater. Spot-on treatments are pre-measured doses in single use pipettes, which you empty onto the back of your dog’s neck. topical . Fipronil disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels. Fipronil is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. Pyriproxyfen. Spotted areas may appear wet or oily for up to 24 hours. In dogs and cats, fipronil is available as a high-volume spray or a low-volume spot-on, with activity against ticks, fleas and ear mites. ACTIVE INGREDIENT: fipronil: 0.29%. Fleas are all-too-common visitors to both cats and dogs. Multiply 0.025 times your pet’s weight for more precise dosage. Mar 18, 2017 - Fipronil for dogs investigates this common insecticide and how it works, and answers your questions about using fipronil on your Lab Veterinary formulations: Frontline Plus® (Merial), Other veterinary formulations: Fipronil is also available without methoprene in, Fipronil and methoprene is used in the control and treatment of all stages of. 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